Biotech
Redrawing the Limits of “Undruggable” Proteins

Redrawing the Limits of “Undruggable” Proteins

For most of modern target-based drug discovery's history, many biologically important targets have been sidelined as undruggable proteins: structural scaffolds and transcription factors with no active site to inhibit, proteins presenting flat surfaces with no pocket...

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Bispecific T-Cell Engagers in Refractory Autoimmune Disease

Bispecific T-Cell Engagers in Refractory Autoimmune Disease

Bispecific T-cell engagers, originally developed to redirect immune responses against cancer, are being investigated as potential therapeutic candidates for treatment-refractory autoimmune connective tissue diseases. A 2026 study published in Nature Medicine reported...

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Medicine Does Not Run on Blood Alone

Medicine Does Not Run on Blood Alone

Prevention-first urine diagnostics will depend not only on how accurately we can measure disease, but on how often and how easily people can be tested. Blood is medicine's default diagnostic medium for good reasons. It circulates through the whole body, carries a...

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The Future of Collagen Hydrogels in Regenerative Medicine

The Future of Collagen Hydrogels in Regenerative Medicine

Collagen hydrogels are still the benchmark for regenerative medicine because they provide cells with an environment that feels biologically familiar. However, the next challenge within this field is no longer proving whether or not collagen works, but in capably...

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New Biology, New Opportunities in Women’s Health

New Biology, New Opportunities in Women’s Health

Capital is moving into women’s health. But the science may give it even more reason to stay. Across the field, substantial unmet need is converging with rapidly advancing science and enormous areas of unexplored biology. Advances in genetics, molecular biology,...

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AI-Discovered Drugs in 2026: The State of Play

AI-Discovered Drugs in 2026: The State of Play

Rentosertib reaches Phase III, Isomorphic Labs raises $2.1 billion, and the EU defers its high-risk AI deadlines. What is still missing for AI-discovered drugs is an approval. AI-discovered drugs entered a different phase in 2026. One molecule has now reached a Phase...

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CAR-T Therapy Explained: A Plain-English Guide

CAR-T Therapy Explained: A Plain-English Guide

CAR-T therapy is one of the most discussed cancer treatments of the past decade, and one of the most widely misunderstood. The name is an acronym. The science involves genetic engineering. The price runs to hundreds of thousands of pounds per patient. This guide...

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