Peptide compounding in the United States has entered a new phase. The Department of Health and Human Services (HHS) will not act against compounders of six unapproved peptides, within strict conditions. The peptides are BPC-157, Epitalon, KPV, MOTS-c, Semax and...
Lilly’s TRANSCEND-T2D-2 trial compared retatrutide with Ozempic 2 mg over 80 weeks. Here is what it found, what it left out and when approval could follow.
The GLP-1 era has given clinicians something they have wanted for decades: medications that produce weight loss approaching what was once possible only with surgery. Semaglutide and tirzepatide routinely deliver reductions of 15% to 20% of body weight in trials, and...
GLP-1 receptor agonists (GLP-1 RAs) have reshaped the treatment of type 2 diabetes and obesity. But the next phase of GLP-1 therapy, and of incretin-based treatment more broadly, is likely to have implications that extend well beyond the approval of another...
Del-desiran next steps after the HARBOR miss: what Novartis has said, the USD 1.9bn impairment and what would settle the DM1 programme’s future.
Depression care continues to evolve as researchers explore why people respond differently to treatment. One area drawing attention is the relationship between the gut microbiome and the brain. Could psychobiotics, which target this connection, offer additional support...
The NHS has made no UK-wide decision on dostarlimab rectal cancer treatment, as of 20 October 2026. The US Food and Drug Administration (FDA) granted accelerated approval on 19 October 2026. The product is GSK’s Jemperli (dostarlimab). Wales has supported off-label...
The Roche Hansoh ADC deal gives Roche rights outside Greater China to a portfolio of early antibody-drug conjugates. In return, Roche pays $400 million upfront and $110 million on the first anniversary. Hansoh Pharmaceutical announced the strategic collaboration and...
Icotrokinra NHS access has no published timetable. As of 14 October 2026, LSDN searches found no UK marketing authorisation for icotrokinra. The drug is approved as Icotyde in the US and EU. The European Commission authorisation was announced on 21 September 2026....
Artificial intelligence is increasingly being integrated into the drug discovery process. From the identification of therapeutic targets to the prediction of molecular interactions and ranking of compounds to be developed further, the power of computational tools...
The Viatris Pacira acquisition buys two US pain products, Exparel and Zilretta, for $36.50 per share in cash. That values Pacira BioSciences at $1.65 billion. Viatris announced the agreement on 8 October 2026. It expects the deal to close by the end of 2026. Closing...
The advent of GLP-1 medications has radically changed the conversation about the treatment of obesity. Effective treatments such as semaglutide and tirzepatide have grown in popularity and use, with more agents in the pharmaceutical pipeline. However, the treatment of...
The life sciences sector has always depended on the quality of evidence behind its decisions. Today, the volume of evidence, and the speed at which it can be analysed, is changing dramatically with artificial intelligence. In September, the National Commission into...
On 2 October 2026, Novartis agreed to license an autoimmune candidate from Abogen for $575 million upfront. Abogen’s release said milestones could add up to about $7.2 billion if every option is exercised. Many headlines led with the combined figure of about $7.8...
Novartis has licensed an mRNA-encoded T-cell engager from Abogen Biosciences of Suzhou, China. Abogen announced the licensing and option agreement through PR Newswire on Friday 2 October 2026. The upfront payment is 575 million US dollars. Milestones could add up to...
AstraZeneca has made a 2 billion US dollar strategic equity investment in Summit Therapeutics. Summit announced the deal through Business Wire on 28 September 2026, after the US market close. The money buys convertible preferred stock. It does not buy a licence to...
Amylin analogues have become one of the most active areas of obesity drug development. Novo Nordisk, Eli Lilly, Roche, Pfizer, AbbVie and AstraZeneca all hold clinical programmes built on the hormone amylin. The most advanced obesity candidate in the class, Novo...
Creating brand value when clinical information is no longer a differentiator The Life Sciences industry is undergoing seismic shifts: expanding drug pipelines, compressed launch timelines, and changing healthcare provider (HCP) and human capital expectations. HCPs...