When treating individuals with inflammatory bowel disease (IBD), either Crohn's disease or ulcerative colitis, I’m often asked: "Will this stop me having children?". Given that IBD affects around 180,000 Australians and is typically first diagnosed between the ages of...
Organ digital twins have moved from mathematical curiosity to funded national priority. Imperial College London now sits close to the centre of that shift. Researchers there have built more than 3,800 anatomically accurate virtual hearts. They have also begun an NHS...
Every year, millions of pathology slides are produced in the UK, most still examined manually under a microscope. This century-old process, though reliable, is no longer fit for purpose. Pathology departments face mounting workforce pressures, with 78% pathologists...
The evolving landscape of cosmetic science is increasingly defined by its convergence with clinical research, challenging long-standing distinctions between aesthetic enhancement and therapeutic intervention. Historically, cosmetics have been confined to products...
South Korea and the United States are both wealthy, technologically sophisticated countries with excellent physicians and world-class hospitals. Yet they placed opposite structural bets on what a health system is for. America bet on treating disease as well as it can...
Clinical decision support is not new, and it does not have to be complex to work. If anything, the simpler it is, the more likely clinicians are to use it. The best-known earlier example is the WHO surgical safety checklist, developed by a team led by Atul Gawande,...
The National Health Service (NHS) is investing heavily in diagnostics. Through Getting it Right First Time (GIRFT) and the rollout of Community Diagnostic Centres (CDCs), millions of patients are getting scans more quickly than ever[1]. The NHS 10 Year Plan has now...
Did you know that your erections can tell you more about your heart health than you might think? Nocturnal erections—those spontaneous erections that happen during sleep—are directly tied to vascular health. When a man stops having them, even for a short period of...
Are we mistaking associations for true biological origins? Despite significant advances in modern medicine, lifestyle diseases such as cardiovascular disease and diabetes continue to rise globally. These conditions are commonly described as “multifactorial,”...
For decades, longevity has been a frontier of scientific exploration, pushing the boundaries of what we believe is possible for human health and lifespan. While incremental progress has been made in understanding the biology of aging, we are now on the cusp of a new...
The application of agentic AI in life sciences reached a tipping point in 2025. Frameworks where specialized agents collaborate on tasks, sharing work, dividing problems, communicating with each other, went from an emerging topic to the predominant conversation. For...
Advances in microbiome science are occurring faster than our ability to apply these insights within complex human systems. While research has dramatically expanded what can be observed within the gut, translating these discoveries into meaningful improvements in...
Words To Begin At age 81, the author has lived a "life of letters" (perhaps three million words) addressing a wide variety of subjects during multiple careers: Systems Engineering (PhD at UCLA in 1976), Military Science (21 years on active duty, in high-tech...
In cardiology and diabetes, we no longer rely on single, in-clinic readings to diagnose complex conditions; instead, remote monitors are used to capture data over a period of time. We’ve seen that the standard of care across medicine is shifting from episodic...
Over the last decade, obesity management has undergone a structural transformation. What was once a field dominated almost exclusively by bariatric surgery has evolved into a far more nuanced metabolic discipline. The rise of GLP-1 receptor agonists and dual incretin...
For much of the history of in-vitro fertilisation (IVF), technological advances have focused overwhelmingly on the egg and the embryo. Advances in ovarian stimulation protocols, time-lapse embryo imaging, genetic testing and cryopreservation have dramatically improved...
Have you considered what it means to have an FDA-approved, life-changing, medical product? It’s nothing short of amazing! However, let me add on to that question, have you considered what it means to have an FDA-approved, life changing, medical product WITHOUT a...
In high-performance populations — elite athletes, tactical operators, founders, executives under sustained cognitive load — resilience is typically framed in terms of cardiovascular output, muscular strength, mitochondrial density or hormonal optimisation. Yet one of...