Collagen hydrogels are still the benchmark for regenerative medicine because they provide cells with an environment that feels biologically familiar. However, the next challenge within this field is no longer proving whether or not collagen works, but in capably...
Is RNA Potency the Problem? Creative Biolabs Webinar on saRNA Delivery
The next breakthrough in RNA therapeutics may depend less on making RNA more powerful and more on solving how efficiently it reaches and functions inside target cells. Creative Biolabs will host the upcoming webinar "Engineering saRNA Delivery Systems for...
Ivonescimab Overall Survival Win Leaves the Key Numbers Undisclosed
Akeso reports an ivonescimab overall survival benefit over pembrolizumab in HARMONi-2, but no hazard ratio, median or data cutoff was disclosed.
New Biology, New Opportunities in Women’s Health
Capital is moving into women’s health. But the science may give it even more reason to stay. Across the field, substantial unmet need is converging with rapidly advancing science and enormous areas of unexplored biology. Advances in genetics, molecular biology,...
Creative Biolabs’ CRISPR Cell Line Development: Plan the Validation First
CRISPR has expanded the possibilities for creating genetically defined cell models, from loss-of-function knockouts to precise knock-ins and stable Cas9-expressing systems. However, successful CRISPR cell line development depends on more than editing efficiency. The...
How Sustainability Can Become a Competitive Advantage in Biomanufacturing
Sustainability has become an expectation across the life sciences industry. Regulations are evolving, customers expect more from suppliers, and companies are making increasingly ambitious environmental commitments. Compliance has helped create a common baseline for...
Improving Oncolytic Virus Development for Cancer Immunotherapy Research
Oncolytic virus development is gaining increasing attention in cancer immunotherapy research because of its ability to combine direct tumor cell killing with immune activation. Unlike conventional therapeutic strategies that focus on one pathway or one target,...
Importance of Targeted Radiotherapeutics in Treating CNS Cancers
Radiation therapy is one of the important tools in the fight against cancer. About 50% of all cancer patients receive radiation therapy. Few modalities have had the same lasting impact across such a broad range of tumor types. In central nervous system (CNS) oncology,...
The Scaling Crisis in Cell and Gene Therapy
There are FDA-approved therapies on the market today that can permanently resolve a disease in a single administration, for a price of one to three million dollars. The reimbursement system responsible for covering that cost was built around medications that people...
The Sourcing Channel Moved East
A record year of out-licensing pulled the West's early pipeline sourcing toward Shanghai and Suzhou. The discount that started it is already being competed away. What outlasts it is a two-source model for global pharma innovation. For most of the past decade, a...
Kailera Therapeutics IPO: A $625M Signal for Biotech
When Kailera Therapeutics priced its initial public offering on 16 April 2026, it did more than raise money. The Kailera Therapeutics IPO set a new benchmark for an industry that had spent the better part of three years in the wilderness. Priced at $625 million, it...
Biotech’s Missing Ingredient: Execution
Biotech has never lacked scientific innovation. What the industry continues to underestimate is how difficult it is to turn promising science into an actual therapy that reaches patients. Over the last several years, I have seen strong assets struggle for reasons...
Hallmarks of Ageing as a Framework: How the Research Field is Evolving
When López-Otín and colleagues published “The Hallmarks of Aging” in Cell in 2013, they did something the field of biogerontology had quietly needed for decades: they created a framework. Nine interconnected processes, from genomic instability and telomere attrition...
Biotech M&A 2026: Every $1B+ Deal so Far and What is Driving Them
Updated 21 October 2026. First published 14 May 2026. Deal values and statuses are as of 21 October 2026. Biopharma M&A 2026 has already outrun last year. J.P. Morgan counts $138.9 billion of upfront M&A across 113 deals by the end of September. That is above...
Using AI to Translate Fragmented Evidence into Formulation Logic
Thesis Early-stage life science development is increasingly constrained not by lack of data, but by fragmented, multi-scale evidence that resists straightforward interpretation. AI systems can assist in structuring this complexity – through literature triage,...
Invisible Architect: How Infrastructure Drives Life Sciences Growth
In the high-stakes world of drug discovery and biomanufacturing, the spotlight typically shines on breakthrough modalities, venture rounds, and FDA milestones. Yet, behind every clinical success is a physical environment that either accelerated the science or quietly...
Why “Hot” Therapeutic Areas Break Traditional Benchmarks
In fast-moving areas like radiopharmaceuticals and precision immunology, the biggest portfolio risk is often not uncertainty itself, but false certainty created by mismatched benchmarks. As life sciences enters a more disciplined cycle, one pattern shows up across...
Longevity Biotech: Separating the Science from the Hype
The Billion-Dollar Race to Slow Ageing Billions of dollars are pouring into the idea that ageing is a disease we can treat. The longevity biotech sector attracted $8.49 billion in private investment across 325 deals in 2024, according to Longevity.Technology's Annual...







